Life & fun · alternatives · 2026

24 alternatives to Esquire Classic Podcast - The Death of Patient Zero

Decisions, consequences -- and love

Below are 24 products that do a similar job, ranked by how close each is in meaning and then by launch-day votes. Esquire Classic Podcast - The Death of Patient Zero launched in 2016; newer entries below may have overtaken it.

1
The Design Review Podcast - The Power of Saying NO!▲61
Defining priorities for good design and saying no!
2016 · its alternatives →
2
Soulection Radio Show #251 ▲65
The people's choice episode 🔥
2016 · its alternatives →
3
StartUp Podcast: Happy Ending (Season 3, Episode 7)▲83
From drug kingpin to solitary confinement (Pt. 1)
2016 · its alternatives →
4
App Guy Podcast Episode ***500*** : We Are All Going To Die!▲70
Skype co-founder talks about the existential threat of A.I
2016 · its alternatives →
5
Hatching - 17: How to meet your heroes▲93
A podcast about the inner workings of Need/Want
2015 · its alternatives →
6
StarTalk Radio - The Science of Love▲58
A cosmic queries episode
2016 · its alternatives →
7
Dudes of Disruption - Episode 20: Sixth Sense: Your Mind and Body in Sync▲60
Our body gives us important signals about our choices
2017 · its alternatives →
8
a16z - A podcast about podcasts▲140
Discussing podcast discovery & community w/ PH & Roman Mars
2015 · its alternatives →
9
Reboot podcast▲205
CEO's discuss psychological challenges w/ Jerry Colonna
2015 · its alternatives →
10
The Reboot Podcast #39: It’s Time for New Choices - with Mary Lemmer▲55
The story of seemingly everything working against her
2016 · its alternatives →
11
Serial Podcast▲177
From This American Life, follow 1 story over a whole season
2014 · its alternatives →
12
Release Notes - 124: Happiness is my default position▲70
Great conversation about personal motivation in this episode
2015 · its alternatives →
13
Nootrobox's THINKING Podcast - Ep. 8: Intelligence and Bacopa with Professor Con Stough▲55
THINK with us!
2016 · its alternatives →
14
Core Intuition - Subscription for Nothing▲66
Marco Arment joins to discuss podcasts, and development.
2015 · its alternatives →
15
Exvangelical Episode 4: On Mental Health: A Conversation w/ Nate Crawford▲55
Coming to terms w/ a messed up subculture.
2016 · its alternatives →
16
Chive Podcast - 40: Men vs Women, relationship pitfalls▲56
Figuring out John's relationship short comings
2015 · its alternatives →
17
Hunt the Truth — S1E1: A hairline fracture▲88
The intro to Microsoft's "Serial"-style Halo podcast
2015 · its alternatives →
18
Zen Founder▲131
A weekly podcast about staying sane while starting up
2015 · its alternatives →
19
Charged Tech Podcast - 001▲80
The inaugural episode on Slack, Apple vs. FBI, and Amazon
2016 · its alternatives →
20
Waking Up with Sam Harris - The Virtues of Cold Blood: A Conversation with Paul Bloom▲55
Sam and Paul explore "the dark side of empathy"
2015 · its alternatives →
21
Dudes of Disruption Ep 10 - The Stories We Make Up About Men and Women▲53
Our automatic beliefs about the opposite sex.
2016 · its alternatives →
22
The Reboot Podcast - 41: Are You Afraid of Your Own Power? ▲55
How John Guydon can’t help but tackle big problems
2016 · its alternatives →
23
Call to Action Podcast▲82
Podcast by Unbounce
2015 · its alternatives →
24
The Infamous Podcast: Ep. 53 - Rebelling Against Outrage▲56
Helping make every fandom accessible for all!
2016 · its alternatives →

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Ranked by how close each launch is in meaning, then by votes. Prices were read from each product’s own site when checked and can change. Refine with your own description →