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    Minicule121

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    BIOS116

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  6. 6AO

    Hi HN - we’re the founders of Ligo Biosciences and are excited to share an open-source implementation of AlphaFold3, the frontier model for protein structure prediction. Google DeepMind and their new startup Isomorphic Labs, are expanding into drug discovery. They developed AlphaFold3 as their model to accelerate drug discovery and create demand from big pharma. They already signed Novartis and Eli Lilly for $3 billion - Google’s becoming a pharma company! (https://www.isomorphiclabs.com/articles/isomorphic-labs-kick...) AlphaFold3 is a biomolecular structure prediction…

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  7. 7MR

    Data visualizations are the bridge between user and data. But building AI agents that can generate visualizations reliably can be very tricky: - simple chart specs can be reliable, but generated charts are often of low quality due to reliance on system defaults; - complex chart specs with explicit details can produce good-looking charts, but they are verbose and agents can struggle with reliability We figured out it is a limitation on the language issue (not just AI capability thing) -- current visualization languages are a bit too low-level for AI agents, requiring them to explicitly make…

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  8. 8IB

    I've been working on nodes.bio - an interactive tool for visualizing biological networks and systems thinking. The tool features interactive network visualization powered by Cytoscape.js, with real-time graph editing and manipulation capabilities. It supports JSON import/export and provides a responsive design that works seamlessly on the desktop (mobile-friendly version coming later). The tech stack combines modern frontend technologies with robust backend architecture. The frontend uses Next.js 14 with TypeScript and Cytoscape.js for the visualization engine. The backend is built with…

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  11. 11
    Portaly267

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  12. 12LI

    Hey all, we felt like existing link-in-bio tools cater to influencers, so we decided to build a tool just for apps and developers. It's called Launch.app! Launch.app is a more opinionated tool than others, built just for apps and app developers. Some features include: - A much better URL: Launch.app/app-name // Launch.app/@username - Verification badging (optional ID / email / location / etc checks) - Aggregate and showcase existing reviews across platforms - Quickly import your styling from existing web site - Dynamic device-based layouts (only show launch…

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  13. 13IV

    Hey HN! This has been my project for a few years now. I recently brought it back to life after taking a pause to focus on my studies. My goal with this project is to separate fluff from science when shopping for supplements. I am doing this in 3 steps: 1.) I index every supplement on the market (extract each ingredient, normalize by quantity) 2.) I index every research paper on supplementation (rank every claim by effect type and effect size) 3.) I link data between supplements and research papers Earlier last year, I took pause on a project because I've ran into a few issues: Legal: Shady…

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  14. 14

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    Fred109

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  18. 18AD

    I've been building computer-use tools for a while, and I quietly launched this about a month ago (122 Stars on GH). I figured it was worth sharing here. Over the last few months, a lot of computer-use agents have come out: Codex, Claude Code, CUA, and others. Most of them seem to work roughly like this: 1. Take a screenshot 2. Have the model predict pixel coordinates 3. Click x,y 4. Take another screenshot 5. Repeat That works, but it's slow, expensive in tokens, and fragile. If the UI shifts a few pixels, things break. And the model still doesn't know what any element actually is. But the…

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  19. 19
    Erbut124

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  20. 20EA

    Hi HN, I’m a solo dev building a clinical search engine to help my wife (a resident physician) and her colleagues. The Problem: Current tools (UpToDate/OpenEvidence) are expensive, slow, or increasingly heavy with pharma ads. The Solution: I built Evidex to be a clean, privacy-first alternative. Search Demo (GIF): https://imgur.com/a/zoUvINt Technical Architecture (Search-Based RAG): Instead of using a traditional pre-indexed vector database (like Pinecone) which can serve stale data, I implemented a Real-time RAG pattern: Orchestrator: A Node.js backend performs…

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  21. 21AA

    aiq lets you use a single CLI command to auto-label text data with a language model API & train an efficient classifier on the labels. Training and inference are super fast (both run on CPU).

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  22. 22IM

    When I read papers, I have to jump between multiple tabs to find the dataset, code, videos, peer reviews, and so on. I tried to fix this with this project. It started as a project just for papers on arXiv, but after its initial success on Twitter (got like 1.9k views: the most I have gotten for a post), I have now expanded it to include other openly available papers from PubMed Central, bioRxiv, medRxiv, and eLife. These papers have been linked with their genes, proteins, diseases, drugs, clinical trials, 3D protein structures, code, and cited and similar papers. This project now has four…

    Jul 2026 · tomesphere.com

  23. 23AF

    I have some chronic medical conditions, and spend a lot of time asking about different drugs and supplements. Wanted to create a resource that others might get value from. It's trained to always provide citations, and to urge people to see their doctor before making major decisions. Open for feedback.

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  24. 24

    The essential tools for biological research, all in one

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