Sapien Labs
In-silico trial engine for psychiatry programs
Sapien Labs launched on May 14, 2026 with 65 votes, #653 of 20,538 launches that month and more than 95% of that year's launches.
What it does
Sapien Labs builds trial-grade external control arms from real-world clinical data so clinical teams can evaluate psychiatry programs without recruiting as many control patients.
Sapien Labs builds digital twins from real-world clinical data to replace part of the control group in Phase 2 and 3 trials. Faster, cheaper trials for sponsors, and a new evidence role for the hospitals and labs that hold the data. Benchmarked first in psychiatry.
We rebuild half of a trial’s control group from real medical records. Sponsors recruit fewer patients, spend less, and reach a readout sooner. Benchmarked first in psychiatry, where the outcomes live in clinical notes. One control arm of a late-stage trial, 1,000 patients, 25 to a block. Footprint counts patients, height is what each one costs. A late-stage trial recruits about 2,000 patients, and half receive a placebo. Enrolling those control patients is the slowest, most expensive part of the study. We rebuild half of the control group from real medical records, as trial-grade synthetic patients. The sponsor recruits fewer people, and every later trial reuses the cohort at lower cost.…from sapien.bio
Does a similar job
all alternatives →
Open-source A/B testing framework2021 · github.com · ▲199Open Source Feature Flags, Experimentation, and Product Analytics - growthbook/growthbook
More life & fun this month
the category →
A free city-building game in your browser. You are the mayor. You know what the city needs. Now get it past the zoning board, the neighbors, the appeals court and the next election.
Life & fun · 2d ago · permit.petercai.com
- IV
Life & fun · 14d ago · tanzaniaeducationproject.org
Turn a phone, tablet or TV into a sign. Type a message and it fills the screen: welcome signs, timers, Wi-Fi passwords and more. No app, no account, free.
Life & fun · 15d ago · bigwords.page
Play a free virtual guitar online with your keyboard or by touch. Slow songs down and see every chord, string and strum. Acoustic, classic, electric and bass.
Life & fun · 9d ago · guitoro.com
Carrier settings from iPhone, Pixel and Galaxy firmware, decoded and compared: APNs, VoLTE, 5G and Wi-Fi Calling per carrier, and what each build changed.
Life & fun · 13d ago · carrierexplode.com
Life & fun · 23d ago · space.bl2.net
Source: Product Hunt launch ↗
Launched alongside, May 2026
the whole month →
Parallel agents, diff reviewer, and multi-model comparisons
Dev tools · May 2026 · kilo.ai
Hey HN, Henry here from Cactus. We open-sourced Needle, a 26M parameter function-calling (tool use) model. It runs at 6000 tok/s prefill and 1200 tok/s decode on consumer devices. We were always frustrated by the little effort made towards building agentic models that run on budget phones, so we conducted investigations that led to an observation: agentic experiences are built upon tool calling, and massive models are overkill for it. Tool calling is fundamentally retrieval-and-assembly (match query to tool name, extract argument values, emit JSON), not reasoning. Cross-attention…
Life & fun · May 2026 · github.com
🌱 Private, quiet space for thinking. Simple app for .md files. - zakirullin/files.md
Dev tools · May 2026 · github.com