AI · alternatives · 2026

24 alternatives to CeLLama – Single cell annotation with local LLMs

A simple R package which helps with annotation of single cell experiments such as single cell RNA-seq. With up and down regulated genes per cell cluster, the local LLM guesses the cell type annotation and creates an overall extensive report.

CeLLama is an R package designed for biologists and researchers conducting single cell RNA-seq experiments. It automates cell type annotation by analyzing up and down regulated genes within each cell cluster, using a… Below are 24 products that do a similar job, ranked by how close each is in meaning and then by launch-day votes. CeLLama – Single cell annotation with local LLMs launched in 2024; newer entries below may have overtaken it.

1
ChatLLaMA – A ChatGPT style chatbot for Facebook's LLaMA▲402
ChatLLaMA is an experimental chatbot interface for interacting with variants of Facebook's LLaMA. Currently, we support the 7 billion parameter variant that was fine-tuned on the Alpaca dataset. This early versions isn't as conversational as we'd like, but over the next week or so, we're planning on adding support for the 30 billion parameter variant, another variant fine-tuned on LAION's OpenAssistant dataset and more as we explore what this model is capable of. If you want deploy your own instance is the model powering the chatbot and build something similar we've open sourced the Truss…
2023 · chatllama.baseten.co · its alternatives →
2
Khoj – Chat offline with your second brain using Llama 2▲565
Hi folks, we're Debanjum and Saba. We created Khoj as a hobby project 2+ years ago because: (1) Search on the desktop sucked; we just had keyword search on the desktop vs google for the internet; and (2) Natural language search models had become good and easy to run on consumer hardware by this point. Once we made Khoj search incremental, I completely stopped using the default incremental search (C-s) in Emacs. Since then Khoj has grown to support more content types, deeper integrations and chat (using ChatGPT). With Llama 2 released last week, chat models are finally good and easy enough to…
2023 · github.com · its alternatives →
3
Llama-dl – high-speed download of LLaMA, Facebook's 65B GPT model▲343
High-speed download of LLaMA, Facebook's 65B parameter GPT model - shawwn/llama-dl
2023 · github.com · its alternatives →
4
Llama 3.3 70B▲347
Llama 405B-level performance, at a fraction of the cost
2024 · developer.meta.com · its alternatives →
5
Embedding Atlas▲150
Hey HN, we're happy to release Mycelium, a JavaScript library for creating graph visualizations of machine learning models or any other directed acyclic graphs. Mycelium powers the graph viewer of the Talaria [0] a research model visualization and optimization system, which was used to optimize the efficiency of Apple Foundation Models [1]. Everything works entirely on the client-side in the browser — we provide a rudimentary ONNX loader out of the box, which you can try by dragging model files into our website. It is also simple to define loaders for your own model formats. The library was…
2025 · apple.github.io · its alternatives →
6
Baserow▲341
Baserow 2.0 introduces workflow automations, the Kuma AI assistant, date dependencies, smarter AI fields, workspace search, and improved security with 2FA.
2022 · baserow.io · its alternatives →
7
Llama▲312
3.1-405B: an open source model to rival GPT-4o / Claude-3.5
2024 · developer.meta.com · its alternatives →
8
Llama 2▲263
The next generation of Meta's open source LLM
2023 · developer.meta.com · its alternatives →
9
WhatsApp-Llama: A clone of yourself from your WhatsApp conversations▲124
Hello HN! I've been thinking about the idea of a LLM thats a clone of me - instead of generating replies to be a helpful assistant, it generates replies that are exactly like mine. The concept's appeared in fiction numerous times (the talking paintings in Harry Potter that mimic the person painted, the clones in The Prestige), and I think with LLMs, there might actually be a possibility of us doing something like this! I've just released a fork of the facebookresearch/llama-recipes which allows you to fine-tune a Llama model on your personal WhatsApp conversations. This adaptation can…
2023 · github.com · its alternatives →
10
Llama2 Embeddings FastAPI Server▲178
Author here. I just wanted a quick and easy way to easily submit strings to a REST API and get back the embedding vectors in JSON using Llama2 and other similar LLMs, so I put this together over the past couple days. It's very quick and easy to set up and totally self-contained and self-hosted. You can easily add new models to it by simply adding the HuggingFace URL to the GGML format model weights. Two models are included by default, and these are automatically downloaded the first time it's run. It lets you not only submit text strings and get back the embeddings, but also to compare two…
2023 · github.com · its alternatives →
11
traceAI▲273
Open-source LLM tracing that speaks GenAI, not HTTP.
Apr 2026 · github.com · its alternatives →
12
Structured output from LLMs without reprompting▲174
Built a tool for transforming unstructured data into structured outputs using language models (with 100% adherence). If you're facing problems getting GPT to adhere to a schema (JSON, XML, etc.) or regex, need to bulk process some unstructured data, or generate synthetic data, check it out. We run our own tuned model (you can self-host if you want), so, we're able to have incredibly fine grained control over text generation. Repository: https://github.com/automorphic-ai/trex Playground: https://automorphic.ai/playground
2023 · automorphic.ai · its alternatives →
13
A terminal spreadsheet editor with Vim keybindings▲126
While speccing out this spreadsheet tool, I realized that I never had to think about the keybindings. It all just came naturally from Vim. Normal/insert/visual modes, hjkl navigation, dd/yy/p, :w, :q. The usual muscle memory works. It supports CSV/TSV import and export, and a native .cell format that preserves formulas. The formula engine handles SUM, AVERAGE, COUNT, MIN, MAX, and IF with range references. The codebase is a Cargo workspace: a pure cell-sheet-core library (no TUI dependency) and a cell-sheet-tui crate on top of ratatui. Early days, but it's usable. To…
Apr 2026 · github.com · its alternatives →
14CD
Cancer diagnosis makes for an interesting RL environment for LLMs▲46
Hey HN, this is David from Aluna (YC S24). We work with diagnostic labs to build datasets and evals for oncology tasks. I wanted to share a simple RL environment I built that gave frontier LLMs a set of tools that lets it zoom and pan across a digitized pathology slide to find the relevant regions to make a diagnosis. Here are some videos of the LLM performing diagnosis on a few slides: (https://www.youtube.com/watch?v=k7ixTWswT5c): traces of an LLM choosing different regions to view before making a diagnosis on a case of small-cell carcinoma of the lung…
Nov 2025 · its alternatives →
15
SwiftAI – open-source library to easily build LLM features on iOS/macOS▲74
We built SwiftAI, an open-source Swift library that lets you use Apple’s on-device LLMs when available (Apple opened access in June), and fall back to a cloud model when they aren’t available — all without duplicating code. SwiftAI gives you: - A single, model-agnostic API - An agent/tool loop - Strongly-typed structured outputs - Optional chat state Backstory: We started experimenting with Apple’s local models because they’re free (no API calls), private, and work offline. The problem: not all devices support them (older iPhones, Apple Intelligence disabled, low battery, etc.). That…
2025 · github.com · its alternatives →
16
Code Llama 70B▲144
New, performant version of Meta's LLM for code generation
2024 · developer.meta.com · its alternatives →
17CJ
Cell.js – A Self-constructing web app framework▲70
2017 · celljs.org · its alternatives →
18WD
Web demo of 13B Alpaca-LLaMA trained on improved Stanford dataset▲42
2023 · lama.nbnl.uk · its alternatives →
19
LLM, a Rust Crate/CLI for CPU Inference of LLMs (LLaMA, GPT-NeoX, etc.)▲45
G'day, HN! I'm one of the maintainers of `llm`. I've been working alongside a trusty group of contributors to bring this project to life, and we're now at a point where we're ready to share it with the world. Large language models (LLMs) are taking the computing world by storm due to their emergent abilities that allow them to perform a wide variety of tasks, including translation, summarization, code generation, and even some degree of reasoning. However, the ecosystem around LLMs is still in its infancy, and it can be difficult to get started with these models. `llm` is a one-stop shop for…
2023 · github.com · its alternatives →
20
OpenSheet▲86
Hi folks. I've been doing some experiments on how LLMs could get more handy in the day to day of working with files (CSV, Parquet, etc). Earlier last year, I built https://datakit.page and evolved it over and over into an all in-browser experience with help of duckdb-wasm. Got loads of feedbacks and I think it turned into a good shape with being an adhoc local data studio, but I kept hearing two main things/issues: Why can't the AI also change cells in the file we give to it? Why can't we modify this grid ourselves? So besides the whole READ and text-to-SQL flows, what seemed…
Feb 2026 · opensheet.app · its alternatives →
21AT
A tool to benchmark LLM APIs (OpenAI, Claude, local/self-hosted)▲55
I recently built a small open-source tool to benchmark different LLM API endpoints — including OpenAI, Claude, and self-hosted models (like llama.cpp). It runs a configurable number of test requests and reports two key metrics: • First-token latency (ms): How long it takes for the first token to appear • Output speed (tokens/sec): Overall output fluency Demo: https://llmapitest.com/ Code: https://github.com/qjr87/llm-api-test The goal is to provide a simple, visual, and reproducible way to evaluate performance across different LLM providers, including…
2025 · llmapitest.com · its alternatives →
22
LLaMA▲118
A foundational, 65-billion-parameter large language model
2023 · research.facebook.com · its alternatives →
23
Llama-8B Teaches Itself Baby Steps to Deep Research Using RL▲39
I've been tinkering with getting Llama-8B to bootstrap its own research skills through self-play. The model generates questions about documents, searches for answers, and then learns from its own successes/failures through RL (hacked up Unsloth's GRPO code). Started with just 23% accuracy on Apollo 13 mission report questions and hit 53% after less than an hour of training. Everything runs locally using open-source models. It's cool to see the model go from completely botching search queries to iteratively researching to get the right answer.
2025 · github.com · its alternatives →
24
SapientML – Generative AutoML for Tabular Data▲82
Generative AutoML for Tabular Data. Contribute to sapientml/sapientml development by creating an account on GitHub.
2023 · github.com · its alternatives →

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Ranked by how close each launch is in meaning, then by votes. Prices were read from each product’s own site when checked and can change. Refine with your own description →