CeLLama – Single cell annotation with local LLMs
A simple R package which helps with annotation of single cell experiments such as single cell RNA-seq. With up and down regulated genes per cell cluster, the local LLM guesses the cell type annotation and creates an overall extensive report.
CeLLama – Single cell annotation with local LLMs launched on July 28, 2024 with 132 votes, #522 of 5,184 launches that month and more than 95% of that year's launches. The site was still online in September 2026, 2 years on.
In plain words
CeLLama is an R package designed for biologists and researchers conducting single cell RNA-seq experiments. It automates cell type annotation by analyzing up and down regulated genes within each cell cluster, using a local large language model to predict cell types and generate comprehensive reports. The tool runs locally, eliminating external dependencies, and streamlines the annotation workflow for single cell studies.
written from the facts on this page · September 2026
From the sources
Cell type annotation with local Large Language Models (LLMs) - Ensuring privacy and speed with extensive customized reports - CelVoxes/ceLLama
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