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Life & fun · July 18, 2012

Plasmyd, a platform for scientists to discuss papers

We're trying to create a space for scientific discussion about papers online, we'd love some feedback. http://plasmyd.com/

Plasmyd, a platform for scientists to discuss papers launched on July 18, 2012 with 6 votes, #106 of 375 launches that month and more than 50% of that year's launches. The site was still online in September 2026, 14 years on.

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What it does

Inherited forms of retinal degeneration, which afflict 1 in 3000 people worldwide, arise primarily from mutations in cells of the eye’s outermost retinal layer (Fig. 1). These include photoreceptor cells—light-detecting neurons in the retina of vertebrate eyes or cells of the retinal pigment epithelium (RPE) a layer of pigmented cells that lies just outside of and supports the photoreceptors. The

Discover innovative adeno-associated virus (AAV) technologies developed to improve retinal gene delivery, photoreceptor transduction, and retinal pigment epithelium targeting. Learn how engineered AAV capsids overcome biological barriers to achieve broad retinal distribution after intravitreal administration. Retinal gene delivery continues to evolve through advanced AAV vector engineering. Modern capsid optimization strategies enable efficient delivery of genetic material into multiple retinal cell populations while improving tissue penetration from the vitreous. These developments are expanding opportunities for ophthalmic research, translational studies, and experimental therapeutic…from plasmyd.com

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