Slay the Spire 2 Guide
Tools & Wiki for Slay the Spire 2
Slay the Spire 2 Guide launched on March 14, 2026.
What it does
The ultimate Slay the Spire 2 resource. Browse 567 cards, 286 relics, class guides, tier lists, and the co-op synergy builder. Updated for EA 2026. Damage Calculator Test card lines with Strength, Vulnerable, Block, Poison, etc. to see if a turn is actually lethal before you commit. Co-op Synergy Builder Pick your team’s classes (2–4 players) and see which co-op cards and class combos synergize best, plus how your team scales as you add more players.
The ultimate Slay the Spire 2 resource. Browse 567 cards, 286 relics, class guides, tier lists, and the co-op synergy builder. Updated for EA 2026.
Cards, relics, class guides, tier lists, and co-op tools — everything you need to climb the Spire. Early Access includes 3 returning characters and 2 brand-new ones. The beginner-friendly warrior. Build massive Block, exhaust cards for powerful bonuses, and recover HP mid-run. Multiple viable build paths make Ironclad the most consistent class. A cunning rogue who weaponizes her discard pile. The new Sly mechanic lets discarded cards play for free, enabling explosive combo turns. Poison stacking remains a core win condition. A malfunctioning robot who channels elemental orbs for passive effects. Lightning deals damage, Frost generates Block, Dark stores burst damage. Focus amplifies…from slaythespire2.space
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