Alternatives
Products that do what ZANE: State-of-the-Art Drugmaking Model does
SOTA AI-native drugmaking assistant with RDKit
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Hey HN, Henry and Roman here - we've been building a cross-platform framework for deploying LLMs, VLMs, Embedding Models and TTS models locally on smartphones. Ollama enables deploying LLMs models locally on laptops and edge severs, Cactus enables deploying on phones. Deploying directly on phones facilitates building AI apps and agents capable of phone use without breaking privacy, supports real-time inference with no latency, we have seen personalised RAG pipelines for users and more. Apple and Google actively went into local AI models recently with the launch of Apple Foundation Frameworks…
2025 · github.com
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Native Swift apps + a real cloud database. One prompt away.
Mar 2026 · nativeline.ai
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For a year or two I've been building a UI library with the aim of making desktop applications fun and easy to write. It is currently written in C/Ruby and uses a custom tree sitter grammar to describe templates. Features include: composable UI components, template directives, event and prop handling, slots, styles and automation capabilities baked in. One of the goals of the project is privileging easy to write custom components via a drawing API over providing a fixed set of components. At the time of this writing it should install on Windows, Mac, and Linux, but sometimes it is hard…
2025 · codeberg.org
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We built SwiftAI, an open-source Swift library that lets you use Apple’s on-device LLMs when available (Apple opened access in June), and fall back to a cloud model when they aren’t available — all without duplicating code. SwiftAI gives you: - A single, model-agnostic API - An agent/tool loop - Strongly-typed structured outputs - Optional chat state Backstory: We started experimenting with Apple’s local models because they’re free (no API calls), private, and work offline. The problem: not all devices support them (older iPhones, Apple Intelligence disabled, low battery, etc.). That…
2025 · github.com
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