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Life & fun · December 15, 2016

Freakonomics Podcast - Bad Medicine, Part 2: (Drug) Trials and Tribulations

How do dangerous drugs make it to market?

Freakonomics Podcast - Bad Medicine, Part 2: (Drug) Trials and Tribulations launched on December 15, 2016 with 60 votes, #1,046 of 3,449 launches that month and more than 50% of that year's launches. The site was still online in September 2026, 9 years on.

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Bad Medicine, Part 2: (Drug) Trials and Tribulations - Freakonomics

How do so many ineffective and even dangerous drugs make it to market? One reason is that clinical trials are often run on “dream patients” who aren’t representative of a larger population. On the other hand, sometimes the only thing worse than being excluded from a drug trial is being included. In the mid-20th century, an exciting new drug hit the market. TERESA WOODRUFF: It’s a small molecule that was produced in West Germany in the late 50s and early 60s. It was a sedative, but not a barbiturate. So it wasn’t addictive, it didn’t clash with alcohol or other drugs and, according to its manufacturer, was entirely safe. They based this claim on the fact that no matter how much of it…from freakonomics.com

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