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Alternatives

Products that do what Open Science, open-source alternative to Claude Science does

Claude Science just launched. It’s a sign AI research is moving toward centralized, closed systems. So we built the opposite: Open Science: a local first, model agnostic AI research workbench. MIT licensed. Fully open. Fully reproducible.

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    Your research partner for rigorous science

    Jul 2026

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    A benchmark evaluating expert-level scientific reasoning

    Dec 2025

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    Platform for measuring and training AI agents

    2016

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    OpenYak114

    The open-source Claude Desktop with any model you want

    Apr 2026

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    Run Claude, Codex & Copilot directly in GitHub & VS Code

    Feb 2026

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    Open-source Claude Work alternative, powered by OpenCode

    Jan 2026

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    Open-source monitoring for machine learning models

    2021

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    Computer use but with OpenAI and Gemini models

    2024

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    OpenMolt132

    Let your code create and manage AI Agents (OpenSource)

    Mar 2026

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    AI workspace for reproducible scientific research

    18d ago · ressearchai.app

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    Local semantic search for AI agents

    30d ago · tryreference.com

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    13,000+ MCP servers, skills & plugins for AI coding agents

    Jul 2026 · codexmarketplaces.com

  13. 13OA

    Claude Code's source map leaked last month. Instead of just reading it, I fed the entire source into Claude Code itself and asked it to extract the core agent loop logic. The result: open-agent-sdk — a drop-in replacement for claude-agent-sdk that's fully open source and doesn't spawn a CLI subprocess. Why this matters if you've built with claude-agent-sdk: claude-agent-sdk is just a thin wrapper around the Claude Code binary. It works, but it's a black box — when something breaks, you're stuck. Every query creates a new Claude Code process. That's fine on a laptop, not fine when you're…

    Apr 2026 · github.com

  14. 14DR

    The first ever AI peer reviewed research article just got approved. It’s kinda crazy how advanced AI have come to replace researchers. I've just been using Deep Research on ChatGPT and Perplexity a lot to write and research complex technical reports for my boss. He loves the reports and it has decreased my workload a ton but I still have some frustrations with it. None of them provide an API that gets me the same quality of output you would with the applications. I wanted something with more control on the LLMs, swappable with the reasoning new models that came out. Not just prompt →…

    2025 · github.com

  15. 15PC

    Hi, We’ve built Pantheon-CLI, an fully open-source project that aims to be the “Python Claude Code + Notebook” — but designed for data analysis instead of just coding. Unlike most AI coding assistants, Pantheon-CLI runs entirely on your machine (or server). No data upload required. It blends natural language and code in a single workflow, keeping variables in memory and letting you switch seamlessly between typing code and asking in plain English. What it does: 1. Chat with your data: Directly process CSV, Excel, AnnData, Pickle, Torch tensors, or any format supported by…

    2025 · github.com

  16. 16ST

    Hey HN community! Over the past year, AI copilots like Cursor and Windsurf have fueled a dramatic shift in software engineering workflows. And yet, many technical users in adjacent fields like data science and analytics have been unable to reap the rewards of this revolution. It turns out that the existing tools are a poor match for analytical workloads. Beyond that Cursor and similar tools have very poor support for Jupyter notebooks, data science is a fundamentally different discipline from software engineering and we believe it requires a correspondingly different tool. We're excited to…

    Sep 2025 · sphinx.ai

  17. 17MO

    Why we built it: • Claude Code: great for coding, but no video/audio support, localhost only • OpenAI SDK: single-model, no native multimedia tools • Both: no integrated DevTools for debugging agent reasoning So, we built Mix as an alternative for multimodal applications. • Native video/audio/PDF analysis tools (via Gemini for vision, Claude for reasoning) • Multi-model routing instead of single-provider lock-in • One-command Supabase setup for cloud deployment (vs localhost-only) • HTTP architecture that enables visual DevTools alongside agent workflows • Go backend: 50-80%…

    Oct 2025 · github.com

  18. 18DO

    Hi HN! I am an undergrad student trying to build interesting things with AI. Recently, I was looking for a dataset I could use for a new project. I realized that it is really frustrating to go through all the government websites (with terrible UX) just to find some usable dataset. I set out to build a GitHub for datasets, named DataHub. Right now, we have more than 1000 datasets from Montréal and New York City, with more cities coming soon (and possible government agencies). All of this is wrapped into a powerful search. It's a breeze to find a dataset to work on. I'd be interested to know…

    2017

  19. 19WB

    Hi HN, I'm one of the creators of Nanobrowser, an open-source Chrome extension that lets you automate web tasks using AI agents. We were inspired by the potential of tools like OpenAI's Operator, but we wanted something that was: -Open-Source:You can see the code, modify it, and contribute to the project. -Browser-Based:No complex setups or server deployments. It runs directly in your browser. -Customizable:You can tailor the agent's behavior to your specific needs. -BYO LLM:Bring your own large language model API key (OpenAI, Anthropic,or even local models), No vendor lock-in. -Privacy…

    2025 · github.com

  20. 20FF

    It uses your local Claude and GitHub CLI and git worktrees, so there's nothing to configure beyond what you already have. Our AI coding workflow was a hodgepodge of scripts and ad-hoc processes, so we built this to centralize and streamline - and most importantly adapt as things change. Some cool features so far (lots more planned): 1. One click github issue to agent working on it. 2. Ratcheting mode, where it watches CI for code review comments and build failures, and automatically fixes them. Would love genuine feedback, bug reports, PRs, suggestions, etc.

    Feb 2026 · github.com

  21. 21AD

    Hey HN, as a former data analyst, I’ve been tooling around trying to get agents to do my old job. The result is this system that gets you maybe 80% of the way there. I think this is a good data point for what the current frontier models are capable of and where they are still lacking (in this case — hypothesis generation and general data intuition). Some initial learnings: - Generating web app-based reports goes much better if there are explicit templates/pre-defined components for the model to use. - Claude can “heal” broken charts if you give it access to chart images and run a…

    Mar 2026 · rubenflamshepherd.com

  22. 22OO

    One coding agent orchestrator UI for Claude and Codex, but actually feels nice. Free, open-source, MIT licensed. Why I built it: - I wanted a lightweight UI as nice as the Codex app, but without the complexity and the custom diffs on the side - I want files and diffs open straight in my editor! - And I wanted both agents - Anthropic + OpenAI — in one place How it works: - No API keys, no OAuth, no separate billing — it just uses whatever you're already logged into. So your Claude Max and ChatGPT/Codex subscriptions both work out of the box. - Talks to Claude Code via the Claude Agent…

    Apr 2026 · github.com

  23. 23HO

    gm gm, We’re excited to show our project, Hive Network, a new frontier for decentralized AI agents that operate both on-chain and off-chain. Our mission is to make AI more powerful and transparent, and we’re inviting you to join us in this revolution. What is Hive Network AI? -- Hive Network AI is a platform where developers can create, deploy, and manage AI agents that function autonomously across blockchain and traditional networks. Our system addresses significant issues in the AI space, such as the lack of transparency, difficulty in monetizing models, and insufficient research funding.…

    2024 · hivenetwork.ai

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    Advancing science, research, and AI without borders

    28d ago · edu.africa

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