Alternatives

Products that do what CUDA, Shmuda: Fold Proteins on a MacBook does

Alphafold3 used to be fodder for HPC clusters; now I've got a port running smoothly on Apple Silicon. If you have an M-series Mac (~2023-present), you can generate protein structures from sequences in minutes. Give it a try! GitHub repo: https://github.com/latent-spacecraft/openfold-3-mlx

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