Alternatives
Products that do what Synergetica – A Modern, End-to-End Genetic Circuit Design Desktop App does
We’ve built Synergetica, an open-source desktop app for end-to-end genetic circuit design. It supports node-based or code-based editing, interactive simulations, and automated DNA sequence generation. You can find the repo and docs here: - GitHub: https://github.com/khokao/synergetica - Docs: https://khokao.github.io/synergetica/
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Explore the DNA of the world’s best product design teams
2018
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Hey HN! We’ve forked Jupyter Lab and added AI code generation features that feel native and have all the context about your notebook. You can see a demo video (2 min) here: https://www.tella.tv/video/clxt7ei4v00rr09i5gt1laop6/view Try a hosted version here: https://pretzelai.app Jupyter is by far the most used Data Science tool. Despite its popularity, it still lacks good code-generation extensions. The flagship AI extension jupyter-ai lags far behind in features and UX compared to modern AI code generation and understanding tools (like…
2024 · github.com
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I made a web game inspired by Geoguessr and Wordle, where you get shown a 3D model of a random human protein each day, and you have to triangulate its gene name using similarity clues. My background is in wet lab molecular biology and I intend this game to be engaging mostly to other biologists. But if you're outside the field, I'm interested to know if you can still solve it with browser use LLMs, and if you learned something interesting doing so. Let me know what you think. I made it with Claude over the last 2 months. My coding experience is limited to basic python data analysis and…
Dec 2025 · geneguessr.brinedew.bio
- 5IV
GitDiagram is an open-source micro dev-tool that I made this past week Given any public GitHub repository it generates diagrams in Mermaid.js with Claude 3.5 Sonnet I extract information from the file tree and README for details and interactivity (you can click components to be taken to relevant files and directories) Also, you can replace "hub" with "diagram" in any repository URL to access its diagram I created this because I wanted to contribute to open-source projects but quickly realized their codebases are too massive for me to dig through manually, so this helps me get started I do…
2024 · gitdiagram.com
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This started as a hard requirement for my TUI-based editor application, it ended up going in a few different directions. A suite of tools that help with semantic code entities: https://github.com/odvcencio/gts-suite A next-gen version control system called Got: https://github.com/odvcencio/got I think this has some pretty big potential! I think there's many classes of application (particularly legacy architecture) that can benefit from these kinds of analysis tooling. My next post will be about composing all these together, an exciting project I call…
Feb 2026 · github.com
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2017 · genewarrior.com
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Hey! This is an open source plasmid and vector (Short, often circular segments of DNA) editor, with features related to primer quality checks, PCR cloning, and protein analysis. I plan to add more restriction-enzyme-based features in the near future. It has some extras like a solution-mixing helper, automatic feature annotation. From a technical standpoint, this is a standalone binary written using the EGUI library in rust. A project goal is performance, with small memory footprint, and small application and file sizes. This is a continuous work-in-progress, and I'm open to any and all…
2024 · github.com
- 12IB
I've been working on nodes.bio - an interactive tool for visualizing biological networks and systems thinking. The tool features interactive network visualization powered by Cytoscape.js, with real-time graph editing and manipulation capabilities. It supports JSON import/export and provides a responsive design that works seamlessly on the desktop (mobile-friendly version coming later). The tech stack combines modern frontend technologies with robust backend architecture. The frontend uses Next.js 14 with TypeScript and Cytoscape.js for the visualization engine. The backend is built with…
2025 · nodes.bio
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One year ago I open-sourced my very first 'real' project and shared it here. I was a college student in my senior year and desperately looking for a job. At the time of sharing it i couldn't even afford a domain and naively let someone buy the one i had my eyes on lol. It's been a hell of a year with this blowing up, me moving to another country, and switching 2 jobs. In a year we somehow managed to hit 26k stars, grow a 1000+ person discord community, and support 37 languages. I couldn't be more grateful for the community that helped this grow, but now i don't know what direction to take…
2025 · drawdb.app
- 14AB
2022 · thesciencegab.com
- 15GB
2025 · attentionmech.github.io
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No gc, No goroutines, Produces small binaries while using the unmodified official go toolchain, and comes with complete Web SDK (generated from w3c/webref). We are building `pcz` to provide a reimagination of Go the language, in an effort to make it suitable for all kinds of programming tasks, and currently you can use it to build efficient web applications in Go using the generated Web SDK (as shown with the live web demo[1]). The journey is just starting, any suggestions? or any critics? [1]: https://primecitizens.github.io/livedemos/10-plat-web/
2023 · github.com
- 18GA
We built Gonzo to make log analysis faster and friendlier in the terminal. Think of it like k9s for logs — a TUI that can ingest JSON, text, or OpenTelemetry (OTLP) logs, highlight and boil up patterns, and even run AI models locally or via API to summarize logs. We’re still iterating, so ideas and contributions are welcome!
2025 · github.com
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A simple R package which helps with annotation of single cell experiments such as single cell RNA-seq. With up and down regulated genes per cell cluster, the local LLM guesses the cell type annotation and creates an overall extensive report.
2024 · github.com
- 20PB
2017 · serotiny.bio
- 21GO
Hi HN, when learning Golang (and topology), I ported a simple GOL in C (https://github.com/Jeadie/GoL) into Go. I then added a bunch of features - Playing on other fundamental polygons (https://en.wikipedia.org/wiki/Fundamental_polygon#Examples_o...) - Considering all possible update rules (of which, there are many). Looking to get back to this project soon. Would love some feedback + ideas.
2022 · github.com
- 22GL
Hi HN! I'm Miguel, an engineer at Gencove. We've just launched a new consumer product that provides genetic insights using low-pass sequencing rather than traditional microarrays. For now we offer 9 polygenic risk scores based on the eMERGE network paper: https://www.nature.com/articles/s41591-024-02796-z After receiving results, you can download your VCF directly (no need to go through support). Happy to answer questions about the tech, accuracy tradeoffs, or how this compares to array-based approaches.
Mar 2026 · gencove.com
- 23GB
Hey HN, I just published v0.1.0 of go-bt and would love some feedback from the Go veterans here. Thanks in advance!
Apr 2026 · github.com
- 24GA
Hi HN — I’ve been working on Gene, a general-purpose, homoiconic language with a Lisp-like surface syntax, but with a core data model that’s intentionally not just “lists all the way down”. What’s unique: the Gene data type Gene’s central idea is a single unified structure that always carries (1) a type, (2) key/value properties, and (3) positional children: (type ^prop1 value1 ^prop2 value2 child1 child2 ...) The key point is that the type, each property name, each property value, and each child can themselves be any Gene data. Everything composes uniformly. In practice this is…
Jan 2026 · github.com
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